Sam, good question. I admit, I fish a totally different type of water here in Kansas so I may be of little help. We fish reservoirs that are 4000 to 17000 acres and relatively featureless other than the channel. In winter we catch our biggest fish near the deepest parts of the lake. The key for me is to cruise the channel or even deep flats thoroughly and watch for the truckload of fish to show up on your screen in sub-40 degree water. After marking a school we generally move to the edge and find something sticking up to key on, but sometimes we slow troll double 1/8-ounce jigs in the area.
As for the larger lakes, the prevailing wind direction of the last few days seems to help and the areas which may collect the flow. I’m sure you’re more than aware of that though. I guess I’d plan out a specific route to search, fire up the sidescan and plan on cruising a lot at a decent speed.