The best bet for decent sized saugers now is on the Iowa side of the river below the dam. In my last couple trips out, the fish have been holding tight to the drop offs, either the first drop from shallow water to the 12-16′ range, or out on secondary drops to the main channel.
The Illinois side below the barge tied up along the lock can also be good. There will probably be a lot of current there, so 3 ways with laarge minnows is a good bet there.
You may want to try a Dubuque rig on either area. This is simply a 3 way using a heavy (5/8 to 1 oz.) jig tipped with a ringworm as your drop weight. Quite often you will find a definate preference for the jig over the live bait, then I would switch up to vertical jigging plastics without live bait.
When vertical jigging plastics, especially superdos and paddletails, you generally want to let the plastic do the work, just drop to bottom, lift 3-12″ from bottom, and hold for 20-30 seconds, then slowly drop to bottom and repeat. Often, the fish will hit as you drop to check for bottom.
Each time on the water, I like to experiment with different baits, colors, and presentations, to see what the fish want on that day. Even if you are catching some fish, it may be good to change up from time to time, as their may well be more fish taking a different look or presentation.
As for colors, the old standbys of Chartruese, orange, green, pink and blue are all good. Chartruese seems to always recieve some attention, even if another color is possibly better.
Be alert for strong back currents which will pull you into some dangerous situations. Look for most of your fish to come in areas of reduced current, or in the backcurrent areas.
Good luck and let us know how you do! I will be out tommorrow, and hopefully will find time to report our findings before the weekend!