I am pretty conservative financially and personally would not recommend to buy new just because you can afford the payment. Even with a low interest rate, you will still be making payments on that $40k+ truck for 6-8 years and it’s highly likely to be under water for a significant portion of that time.
I did a bunch of research and narrowed my options to used tundras and F150’s. Ended up with a ‘14 F150 with the 5.0 engine and low miles and couldn’t be happier.
I would much rather owe money on a truck with a warranty than one without or nearing the end. If I was a w2 employee I would likely never buy a newer truck. Now if your self employed it makes a lot of sense to buy new especially with the tax breaks now.