Adding plain salt can help lower stress levels and replace electrolytes. I too was having issues until I dumped in about 3/4 of a cup into my 55 gal aquarium. Since I started adding salt I have not had near the dead minnows I had before. It used to be that every fathead was dead within a week and now I loose a few the first few days. The strange thing is I only had problems with fatheads. I have kept leftover shiners alive for months without any issues. I’m assuming like was mentioned before that they come from the bait shop disease ridden.
Have seen the same thing myself this winter, get a scoop of fatheads plus a dozen shiners and a week later I’m at less than half my fatheads but have lost maybe 1-2 shiners, glad I’m not the only one who had this happen.
I’m just using a 5 gallon bucket and fish tank supplies from PetSmart, dragging back and forth from uninsulated garage to basement bathroom as needed. Have had success going about three weeks each batch this way and I call it a win. Keeping them cold, under 50 degrees, is the best way I’ve found. Hope this helps, good luck.