Depends upon the lake. Last year on a smaller lake we got into gills, crappies, and even a nice walleye on the same spot.
Hard to beat walleyes on Ottertail at first ice, though you may have to do a bit of searching.
One tip that worked last year when targeting fish in weed lines was to set up where a lot of air bubbles were visible. For some reason, that was key. Once we got some snow cover, it got a lot harder to find those spots so more drilling and searching was required.