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I wonder if the deer had an injured rear leg. I saw a hunting show one time that said that the antlers will grow like that when the opposite rear leg is injured. So it may not be bad genes but something else.
It almost looks like there could have been damage to the pedicel(sp). Look at how the horn comes out lower than the other side. Could very well have been head trauma.
I beleive that the buck in the top picture had been injured. The base of the horn looked infected and the deer stunk, but that could have been because the guy gutting it had a little trouble